Clinicopathological study if Helicobacter pylori eradication in adult patients with idiopathic thrombocytopenic purpura *
There have been many reports that Helicobacter pylori（H. pylori）eradication induces platelet recovery in adult patients with idiopathic thrombocytopenic purpura（ITP）. In our 22 adult ITP patients who were H. pylori positive, H. pylori eradication resulted in hematological complete remission in 56％. One reason for platelet count recovery may be cross-reaction for platelets by anti-H. pylori IgG. However, in some patients there was no platelet count recovery with the disappearance of anti-H. pylori IgG suggests that other factors may exist. In our study, eradication of H. pylori had no obvious adverse effects. This suggests that H. pylori eradication could be useful for the first line therapy of H. pylori positive ITP patients. (Accepted on November 22，2005) Kawasaki Igakkaishi 31(４):243－248，2005
