Diagnostic criteria of primary OP, and guidelines on the management and treatment of glucocorticoid-induced osteoporosis *
With increasing aged-population, the prevalence of osteoporosis is increasing. As osteoporosis leads to fragility fracture, and consequently decreased level of QOL, its early diagnosis, fracture risk assessment, and prevention and treatment are important. Bone strength primarily reflects the integration of bone density and bone quality. In 2000,“Diagnostic Criteria, BMD-based, for Primary Osteoporosis”in Japanese women was established. Bone quality refers to architecture, turnover, damage accumulation（e.g. microfractures), and mineralization. In addition,“Guidelines for the Use Biochemical Markers of Bone Turnover in Osteoporosis”was proposed. As glucocorticoid induces complication of osteoporosis frequently,“Guidelines on the Management and Treatment of Glucocorticoid-induced Osteoporosis”was developed. In this review, these criteria and guidelines have been described. We hope this review will be used for clinical practice of osteoporosis.
