Primary testicular lymphoma diagnosed as recurrence eight years after initial complete remission *
The patient was a 73-year-old man, who experienced left-sided painless scrotal swelling in 1995. Upon examination, a tumor was confirmed in the left testis. After a left orchiectomy, a histopathological examination revealed a diffuse large B cell lymphoma（DLBCL）, and a diagnosis of primary testicular lymphoma（PTL）was made. He received six courses of chemotherapy（THP-COP）, intrathecal administration of anticancer drugs, and radiotherapy（30Gy）to the contralateral testis, resulting in the achievement of complete remission. In July 2003（eight years after the first hospital visit）, right-sided painless scrotal swelling and nasal obstruction developed. A right orchiectomy was performed, and a diagnosis of DLBCL was made. After chemotherapy（biweekly THP-COP）combined with rituximab, a second complete remission was achieved, which has been maintained until now. Because PTL is liable to recur or metastasize, it is classified as a malignant extranodal lymphoma with a poor prognosis. This patient experienced recurrence at the same site after eight years, despite prophylactic radiotherapy to the contralateral testis. Since PTL may recur even after long-term remission, prolonged careful follow-up is needed. （Accepted on March 24，2005）
