Bone mass measurement of cortical bone of the tibia with quantitative ultrasound: Correlation with peripheral quantitative CT in clinical and cadaveric subjects *
Quantitative ultrasound (QUS) is a well-known method with good precision which can be used to evaluate bone mass simply from the speed of sound (SOS) without radiation. The Sound Scan 2000 (Omron Myriad, Israel) is a unique QUS device for which the tibial cortical bone has been adopted as a measurement site. Other QUS dcviccs measure SOS in the calcaneus which is composed mainly of trabecular bone. However, the accuracy of measurement with Sound Scan 2000 has not been clarified sufficiently. Combined measurements with peripheral quantitative computed tomography (pQCT) (Densiscan-1000, Scanco Medical AG, Switzerland.). with which bone mineral density (BMD) in the tibial cortical bone can be measured and whose accuracy of measurement has already been established, and the Sound Scan 2000 were made. For the study with cadaveric subjects, 10 lower legs were used, and correlations between the SOS of cortical bone in the middle diaphysis of the tibia with the Sound Scan 2000. and the parameters of bone mass in the distal metaphysis (19-33.5 mm below the distal end), distal diaphysis (62-70.5 mm below the distal end), and middle diaphysis of the tibia with pQCT were studied. It was shown that the SOS correlated with BMD, volume and thickness in the middle diaphysis of cortical bone. For the study with clinical subjects, measurements were performed in 46 normal women, and correlations with the SOS of cortical bone in the middle diaphysis of the tibia with the Sound Scan 2000, and the parameters of bone mass in the right distal metaphysis and distal diaphysis of the tibia with pQCT were studied. The SOS showed higher correlation with BMD in the distal diaphysis than in the distal metaphysis, and strong correlation with cortical area or thickness. Thus, it was shown that the SOS of the cortical bone reflected BMD and the thickness of cortical bone. (Accepted on October 20. 2000) Kawasaki Igakkaishi 26(4) : 259―266, 2000
