The Effect of Tape Stripping on the Fate of Intradermally Injected Dinitrophenylated Isogeneic Epidermal Cells and Allogeneic Epidermal Cells in Guinea Pigs
DNP-iso ECs or alio ECs were injected intradermally into normal or tape stripped ear skin of inbred JY-1 strain guinea pigs. The fate of the injected cells was histologically examined. The cells proliferated in the dermis, formed EC nests with central keratinization and then elicited a reject reaction associated with necrosis of the epidermal structures in both normal and stripped skin. The suppressive effect of the tape stripping treatment on the reaction was not observed. The significance of the findings is discussed.
