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Online edition:ISSN 2434-3404

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EXPERIMENTAL STUDY ON THE SUSCEPTIBILITY TO KLEBSIELLA PNEUMONIAE IN THE MOUSE WITH INJURED LUNG

In order to confirm the enhancing effect of tracheo-bronchopulmonary damage upon the susceptibility to infection, varying amounts of Klebsiella pneumoniae, strain B-54, were aspirated or inhaled to the mice having formaldehyde injured lungs. As judged from higher death rates from pneumonia, these animals were found to be more susceptible to the transnasal inoculation than normal controls. For the demonstration of difference in the susceptibility between two groups, the dose of bacilli inoculated played a crucial role.

Author
Matsushima T, et al
Volume
7
Issue
3
Pages
147-151
DOI
10.11482/KMJ-E7(3)147

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