EOSINOPHILIC LYMPHOFOLLICULAR GRANULOMA IN PAROTID GRAND (KIMURA’S DISEASE): A Report of Two Cases.
Two cases of eosinophilic lymphofollicular granuloma are reported, one developing in a 48 year old female and the other in a 19 year old male. The granuloma had recurred after previous surgery in both cases. This entity is seen mainly in young males and is accompanied by such findings as eosinophilia and enlargement of lymph nodes or presence of subcutaneous masses. There are such histological findings as hyperplasia of lymph follicles and marked eosinophilic infiltration, but the true nature of this disease is yet unknown. In the two cases reported, there was a mass in the region of the parotid gland and enlargement of the cervical lymph nodes on the same side which made the authors suspect malignant tumor of the parotid gland at first. This lesion proliferates by infiltration, and if the tumor is enlarged, it is difficult to make total extirpation. As there is a strong tendency of recurrence even after surgery and although temporarily it responds to corticosteroids and radiation therapy, it is considered this disease falls in the realm of internal medicine rather than surgery. In Japan, this entity is known as Kimura's disease. The general physical condition is good and there have been no reports of death attributable to it to date.
