HISTOLOGICAL STUDY ON RETEST REACTION IN CONTACT SENSITIVITY TO DNCB
Chronologic development of histologic changes of the retest reaction was investigated in guinea pigs with contact sensitivity to DNCB. There was a striking influx of eosinophils into skin accompanied by varying stage of vacuole in epidermis, well correlated with the gross reaction, i.e. beginning at about three hours and maximal at about nine hours after antigenic challenge. The significance of these findings is discussed.
