CHANGES OF pH OF BLOOD DILUTED WITH PLASMA SUBSTITUTES IN VITRO
Changes of pH of dog's arterial blood (7.41) by in vitro dilutions (1:1, 1:3, 1:7, 1:15) with five types of modified fluid gelatin (MFG) solution and four types of dextran solution were observed. In general, dilution with MFG solution (4 %) decreased pH of blood relatively greater than that with dextran solution, namely pH of blood was below 7.21 at 1:15 dilution. Dilution with the more concentrated MFG solutions (7 % and 10 %) induced the more severe decrease of pH. Dilution with dextran in 5 % glucose solution induced great decrease of pH which was below 6.80 at 1:7 dilution, while dilution with dextran in saline, lactated Ringer's or acetated Ringer's solution caused slight decrease of pH of blood and remained above 7.31 at 1:15 dilution.
