Challenge for Myopia-Progression Control using Spectacles
An overview of myopia control studies using spectacles performed over the past 25 years is provided herein. To address defocus behind the retina (a key factor triggering excessive elongation of the eye), progressive addition lenses (PALs) or peripheral-aspherized PALs have been used in a number of randomized clinical trials (RCTs). While RCTs reported statistically significant inhibitory effects, they were not clinically meaningful. In response, multiple segments lenses based on the defocus incorporated theory (DIMS) were developed and evaluated in RCTs. DIMS lenses achieved superior effects, showing an inhibitory ratio > 50%. By controlling excessive axial elongation during childhood, the spectacles may reduce the risk of severe eye diseases associated with high myopia in adulthood.
