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Online edition:ISSN 2758-089X

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Improvement of Psoriatic Erythroderma by Combination Therapy Consisting of Systemic Etretinate and a Corticosteroid, Photochemotherapy, and a Topical Corticosteroid and Vitamin D3

A 31-year-old Japanese woman was admitted to our hospital with diffuse erythroderma with generalized desquamation and arthritis in the ankle joints. Based on a skin biopsy specimen which revealed the histological picture of psoriasis, a diagnosis of psoriatic erythroderma was made. Treatment with a topical corticosteroid and systemic methotrexate was ineffective. Oral cyclosporine was effective, but it was discontinued because of exacerbation of a respiratory tract infection. Treatment with oral prednisolone relieved her joint pain, but manic-depressive psychosis developed, and lithium carbonate was given orally. Topical psoralen with ultraviolet A radiation (PUVA) treatment in combination with the systemic and topical corticosteroids, topical vitamin D3, and systemic etretinate controlled her psoriasis and arthritis.

著者名
INAOKI M, et al
30
1-2
37-42
DOI
10.11482/KMJ30(1.2)37-42.2004.PDF

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