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Online edition:ISSN 2758-089X

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Clinical effect of sulbactam/ampicillin on community-acquired pneumonia with positive Streptococcus pneumoniae urinary antigen test

We investigated the efficacy of intravenous penicillin (sulbactam/ampicillin: SBT/ABPC) in adult patients with positive Streptococcus pneumoniae urinary antigen test requiring hospitalization. We administered 3g of SBT/ABPC intravenously in the morning and evening for 7-14 days to 32 adult community-acquired pneumonia patients with positive Binax NOW® S. pneumoniae urinary antigen. Clinical efficacy, bacteriological efficacy, and side effects of these patients were prospectively examined. We observed clinical efficacy in a total of 28 of 32 patients (87.5%); 24 of 26 moderate patients (92.3%), and four of six severe patients (66.7%). Side effects were drug eruption, increased GOT, increased AMY, and decreased WBC, observed in one patient each; however, all were mild. SBT/ABPC is extremely useful in patients with positive S. pneumoniae urinary antigen test requiring hospitalization (Accepted on February 12, 2013)

著者名
OKIMOTO N, et al
39
3
61-64
DOI
10.11482/2013/KMJ39(3)61-64.2013.pdf

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