Selenium Deficiency in Crohn’s Disease on Long-term Enteral Nutrition: Report of a Case.
A case of Crohn's disease accompanied by selenium deficiency during enteral nutrition is reported. Exclusive enteral nutrition was chosen as the method of therapy after a diagnosis of Crohn's disease was made. Two years later, palpitation and deformity of the fingernails developed. A diagnosis of selenium deficiency was made based on reductions in the serum selenium concentration and glutathione peroxidase activity. After selenite supplementation, those normalized with subsequent improvement in clinical symptoms. There appears to be some danger of selenium deficiency for Crohn's disease patients on long-term exclusive enteral nutrition lacking in selenium.