Treatment of Neuroleptic-Induced Tardive Dystonia with Dantrolene: A Case Report
We present a case of neuroleptic-induced tardive dystonia in a male schizophrenia in which treatment with dantrolene was associated with improvement. The dystonia appeared 12 months after the patient had began neuroleptic treatment. He did not respond to anticholinergic or other medications, so dantrolene was added to the regimen. After the patient had taken 50 mg of oral dantrolene, his cervical dystonia improved. Dantrolene may be beneficial in the treatment of some patients with tardive dystonia, but further research is necessary.