Treatment of Hepatocellular Carcinoma with Transcatheter Chemo-embolization Using Iodized Oil
Four patients with hepatocellular carcinoma (HCC) were given either an intraarterial injection of iodized poppyseed oil (Lipiodol) alone, an emulsion of iodized oil and doxorubicin hydrochloride (Adriamycin), or the emulsion plus gelatin sponge (Spongel) particles. Hepatic resection was subsequently performed. The frequencies of necrosis in the tumors were evaluated in the cut surface of resected specimens. The emulsion plus gelatin sponge demonstrated the best therapeutic effects. Although the emulsion led to partial necrosis of the tumor, iodized oil alone had practically no therapeutic effect.
