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Online edition:ISSN 2758-089X

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Reducing Effect of Steroids on Fragility of Human Erythrocytes Detected by a Prompt Hemolysis Test

Steroids reduced the fragility of human eythrocytes. Progesterone was so far the most effective (1.25×10-5~1.0×10-4M). This can be detected by a prompt hemolysis test, but not by the currently-used hemolysis test (Sanford method). (14C) progesterone can be easily uptaken and released by the erythrocyte membrane. Discocytes were transformed into stomatocytes and spherocytes by the addition of progesterone (5×10-5 M~2×10-4M).

著者名
Kaya H
11
1
17-23
DOI
10.11482/KMJ-E11(1)17

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