The Quantitative Changes of the Plasma Fibronectin (FN) with Aging
Using an enzyme linked immunosorbent assay (ELISA), we investigated the changes in the amount of human plasma fibronectin (FN) with aging. The increase of plasma FN concentration with aging was slight up to about 50 years of age. Between 60 and 100 years there was a marked increase of plasma FN concentration with aging. The plasma FN concentration from three patients with Werner's syndrome showed higher value than the average of their age group.