Disseminated Astrocytoma. A Neuropathologc Study
Neuropathologic findings of a case of disseminated astrocytoma are described in a 47-year-old woman who had progressive mental deterioration, gait disturbance and urinary incontinence. She became comatose and tetraplegic in the later stage of a one year course. Neuropathologically, the brain was of normal size and neoplastic astrocytes of low malignant nature and variable cellularity were scattered throughout the brain, which was examined from the frontal lobe to the medulla oblongata. The tumor cells were especially prominent in the subpial and subependymal regions. Our case was thought to be intermediate between gliomatosis cerebri and multicentric glioblastoma.