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Online edition:ISSN 2758-089X

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Effects of Treatments for Experimental Bone Tumor on Prostaglandin E Level and Bone Scintigrams

The role of Prostaglandin E (PgE) level was studied experimentally as follows: 1) intrahepatic implantation of VX-2, 2) intravenous injection of VX-2, 3) effect of treatments on intramedullary implanted VX-2. The levels of PgE in intrahepatic and intravenous transplantation were not higher than that of intramedullary transplantation. Mitomycin C (MMC) did not reduce the PgE level and appearance time of bone scan abnormality was the same as that of untreated animals. A combination of indomethacin and MMC caused a delay in appearance time of bone scan abnormalities.

著者名
Otsuka N, et al
9
3
151-155
DOI
10.11482/KMJ-E9(3)151

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