THE COMPARATIVE STUDIES ON THE SURFACE OF CELLS INFECTED WITH TYPE 1 AND TYPE 2 HERPES SIMPLEX VIRUS BY SCANNING ELECTRON MICROSCOPY
The differences between in the surface of type 1 and type 2 herpes simplex virus (HSV) infected cells were noticeable, when these cells were observed in detail by scanning electron microscopy (SEM). 1. Whereas many 100-250 nm particles on the type 1 HSV infected human embryo fibroblast (HE) cells surface were seen, a few on the type 2 infected cells. Therefore we can easily distinguish these two strains. 2. The evidence is applicable in the laboratory strains and the freshly isolated strains from the patients. The result obtained from this observation might indicate that these differences are significant as biological markers and provide an useful evidence in the laboratory diagnosis of herpes infection.