THE SIGNIFICANCE OF ABNORMAL POLYGRAPHIC FINDINGS IN ISCHEMIC HEART DISEASE AND PRIMARY MYOCARDIAL DISEASE. CORRELATION OF LEFT VENTRICULAR SYSTOLIC TIME INTERVALS WITH CORONARY AND LEFT VENTRICULAR ANGIOGRAPHIC FINDINGS.
The results of coronary angiography (CAG) and left ventriculography (LVG) were correlated with measurements of left ventricular systolic time intervals (STI) in ischemic heart disease (IHD) and primary myocardial disease (PMD) in 35 subjects. All 7 patients with IHD and abnormal wall motion, and all 7 patients with PMD showed significantly (p<0.01) low values of ET/ PEP and significantly (p<0.01) high values of ⊿PEP. These polygraphic parameters varied widely in IHD patients with normal wall motion, with angina pectoris, or with myocardial infarction, and did not correlate with the number of vessels involved. Q-II and ET were poorly correlated with the severity or type of myocardial disease. The correlation of ejection fraction with ET/PEP and with PEP was good: correlation coefficients were r=+0.66 and r = -0.70, respectively. From these results it is concluded that 1) if a patient has an ET/PEP of more than 2.45 or a ⊿PEP of less than +13 msec, IHD with abnormal wall motion or PMD is most unlikely, and that 2) abnormal values of ET/PEP and ⊿PEP are related to the abnormally low ejection fractions which are found in IHD with abnormal wall motion or in PMD.